“Africa has the greatest amount of phenotypic variability in skin color, and yet it’s been underrepresented in large scale endeavors.”

Posted in Excerpts/Quotes on 2017-12-05 00:44Z by Steven

Africa has the greatest amount of phenotypic variability in skin color, and yet it’s been underrepresented in large scale endeavors,” said Alicia Martin, a postdoctoral scientist in the lab of Broad Institute member Mark Daly. “There are some genes that are known to contribute to skin pigmentation, but by and large there are many more new genes that have not been discovered.”

David Cameron, “Skin pigmentation is far more genetically complex than previously thought,” Broad Institute, November 30, 2017. https://www.broadinstitute.org/news/skin-pigmentation-far-more-genetically-complex-previously-thought.

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Skin pigmentation is far more genetically complex than previously thought

Posted in Africa, Articles, Health/Medicine/Genetics, Media Archive on 2017-12-03 22:33Z by Steven

Skin pigmentation is far more genetically complex than previously thought

Broad Institute
Massachusetts Institute of Technology, Cambridge, Massachusetts
2017-11-30

David Cameron, Director of Communications/Media Relations


Credit : Brenna Henn
South African individuals in a household that exemplify the substantial skin pigmentation variability in the Khomani and Nama populations. Picture taken with consent for publication.

By studying an African population underrepresented in most datasets, researchers find genetic complexity of pigmentation varies by latitude

Many studies have suggested that the genetics of skin pigmentation are simple. A small number of known genes, it is thought, account for nearly 50 percent of pigment variation. However, these studies rely on datasets that heavily favor northern Eurasian populations—those that reside mostly in higher latitude regions.

Reporting in the November 30 issue of Cell, researchers from the Broad Institute of MIT and Harvard, Stanford University, and Stony Brook University report that while skin pigmentation is nearly 100 percent heritable, it is hardly a straightforward, Mendelian trait. By working closely with the KhoeSan, a group of populations indigenous to southern Africa, the researchers have found that the genetics of skin pigmentation become progressively complex as populations reside closer to the equator, with an increasing number of genes—known and unknown—involved, each making a smaller overall contribution.

“Africa has the greatest amount of phenotypic variability in skin color, and yet it’s been underrepresented in large scale endeavors,” said Alicia Martin, a postdoctoral scientist in the lab of Broad Institute member Mark Daly. “There are some genes that are known to contribute to skin pigmentation, but by and large there are many more new genes that have not been discovered.”

“We need to spend more time focusing on these understudied populations in order to gain deeper genetic insights,” said Brenna Henn, assistant professor in the Department of Ecology and Evolution at Stony Brook University who, along with Martin, is a co-corresponding author…

Read the entire article here.

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Helen Grant first black female minister in the UK

Posted in Articles, New Media, Politics/Public Policy, United Kingdom, Women on 2012-09-09 00:48Z by Steven

Helen Grant first black female minister in the UK

Afro-Europe International Blog
2012-09-09

Helen Grant MP has been made a Minister in David Cameron’s Ministerial reshuffle this September. She is now the first female black cabinet Minister in the UK.

Grant, 50, was born in London to an English mother and Nigerian father, but grew up in a single parent family after her parents separated and her father emigrated to the United States…

Read the entire article here.

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